中央研究院原子與分子科學研究所 - 研究人員資訊 (Institute of Atomic and Molecular Sciences, Academia Sinica)

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賴品光博士 (生物物理與分析技術組)

奈米生物科技與分子影像實驗室

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02-23668204

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408實驗室

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02-23668244

代表作

Magoling, B., Chen,Y., Wu, A.Y., Wong, W.W., Chou, S.T., Huang, H., Sung, Y., Hsieh, H., Huang, P., Lee, K., Huang, K., Chen,R., Chen,Y., Lai, C.P.* (2023). Membrane protein modification modulates big and small extracellular vesicle biodistribution and tumorigenic potential in breast cancers in vivo. Advanced Materials. 35(13): e2208966.
Chien, J.C., Badr, C.E.*, Lai, C.P.* (2021). Multiplexed bioluminescence-mediated tracking of DNA double strand break repairs in vitro and in vivo. Nature Protocols. 16, 3933-3953. *Co-last authors.
Wu, A.Y., Sung, Y., Chen, Y., Chou, S.T., Guo, V., Chien, J.C., Ko, J.J., Yang, A.L., Huang, H., Chuang, J., Wu, S., Ho, M., Ericsson, M., Lin, W., Cheung, C.H.Y., Juan, H., Ueda, K., Chen, Y., Lai, C.P. (2020). Multiresolution imaging using bioluminescence resonance energy transfer identifies distinct biodistribution profiles of extracellular vesicles and exomeres with redirected tropism. Advanced Science. 7 (19): 2001467-83.
Chien J.C., Pinkham, K., da Hora, C.C., Tabet E., Badr C.E.*, Lai, C.P.* (2020). Multiplexed bioluminescent reporter enables real-time tracking of DNA double strand break repair dynamics in vitro and in vivo. Nucleic Acids Research. 48 (17): e100-117. *Co-last authors.
Reátegui, E.,* van der Vos, K.E.,* Lai, C.P.,* Zeinali, M., Atai, N.A., Aldikacti, B., Floyd Jr., F.P., Khankhel, A.H., Thapar, V., Hochberg, F.H., Sequist, L.V., Nahed, B.V., Carter, B.S., Toner, M., Balaj, L., Ting, D.T., Breakefield, X.O., Stott, S.L. (2018). Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Nature Communications, 9 (1): 175-186.
Pucci, F., Garris, C., Lai, C.P., Newton, A., Pfirschke, C., Engblom, C., Alvarez, D., Sprachman, M., Evavold, C., Magnuson, A., von Andrian, U.H., Glatz, K., Breakefield, X.O., Mempel, T.R., Weissleder, R., Pittet, M.J. (2016). SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions. Science, 352 (6282): 242-6.
Lai, C.P., Kim, K.Y., Badr, C.E., Mempel, T.R., Tannous, B.A., Breakefield, X.O. (2015). Visualization and tracking of tumor extracellular vesicles delivery and RNA translation using multiplexed reporters. Nature Communications, 6: 7029.1.
Zaborowski, M., Breakefield, X.O., Lai, C.P. (2015). Extracellular vesicles: composition, biological relevance and methods of study. Bioscience, 65 (8): 783-797.
Lai, C.P., Mardini, O., Ericsson, M., Prabhaker, S., Maguire A., Chen, J.W., Tannous, B.A., Breakefield, X.O. (2014). Dynamic biodistribution of extracellular vesicles in vivo using a multimodal reporter. ACS Nano, 8 (1): 483-94.
Lai, C.P., Bechberger, J., Naus, C. (2009). Pannexin2 as a Novel Negative Growth Regulator in C6 Gliomas. Oncogene, 28 (49): 4402-8.
Lai, C.P., Bechberger, J., Thompson, R.J., MacVicar, B., Bruzzone, R., Naus, C. (2007). Tumor-suppressive Effects of Pannexin1 in C6 Gliomas. Cancer Research, 67 (4): 1545-54.

目前位置：本所人員 / 研究人員/ 賴品光

中央研究院 原子與分子科學研究所

賴品光 博士 (生物物理與分析技術組)

賴品光博士 (生物物理與分析技術組)