Dr. Chia-Lung Hsieh (Biophysics and Bioanalytical Technology)
Tel of Office:
+886-2-2362-4956
Tel of Lab.:
+886-2-2362-4955
Selected Publications
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Cheng CY, Hsiao YT, Wong KL, Tseng HH, Tsao Y, Hsieh CL*, “Temporal variance mapping with machine learning for label-free 3D chromatin imaging using optical interferometric microscopy,” Biomedical Optics Express 17(2), pp. 527-543 (2026).
- Tsai SF, Hsieh CL*, “Ultrasensitive bright-field microscope enables label-free single-protein detection,” Optics Letters, 50(24), pp.7520-7523 (2025).
- Brooks NJ, Liu CC, Hsieh CL*, “Point spread function engineering for spiral phase interferometric scattering microscopy enables robust 3D single-particle tracking,” ACS Photonics 11(12), pp. 5239-5250 (2024).
- Hsiao YT, Liao IH, Wu BK, Chu HP, Hsieh CL*, "Probing chromatin condensation dynamics in live cells using interferometric scattering correlation spectroscopy," Communications Biology 7: 763 (2024).
- Hsiao YT, Tsai CN, Chen TH, Hsieh CL*, "Label-free dynamic imaging of chromatin in live cell nuclei by high-speed scattering-based interference microscopy," ACS Nano 16(2), 2774 (2022).
- Huang YC, Chen TH, Juo JY, Chu SW, Hsieh CL*, "Quantitative imaging of single light-absorbing nanoparticles by widefield interferometric photothermal microscopy," ACS Photonics 8(2), 592 (2021).
- Liao YH, Lin CH, Cheng CY, Wong WC, Juo JY, Hsieh CL*, "Monovalent and oriented labeling of gold nanoprobes for the high-resolution tracking of a single membrane molecule," ACS Nano 13(10), 10918 (2019).
- Cheng CY, Liao YH, Hsieh CL*, "High-speed imaging and tracking of very small single nanoparticles by contrast enhanced microscopy," Nanoscale 11, 568 (2019).
- Cheng CY, Hsieh CL*, "Background estimation and correction for high-precision localization microscopy," ACS Photonics 4(7), 1730 (2017).
- Huang YF, Zhuo GY, Lin CH, Hsieh CL*, "Label-free, ultrahigh-speed, 3D observation of bidirectional and correlated intracellular cargo transport by coherent brightfield microscopy," Nanoscale 9 6567 (2017).
- Huang YF, Zhuo GY, Chou CY, Lin CH, Chang W, Hsieh CL*, "Coherent brightfield microscopy provides the spatiotemporal resolution to study early stage viral infection in live cells," ACS Nano 11(3), 2575 (2017).
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Latest update 2026-02-05 13:07:26
Institute of Atomic and Molecular Sciences Academia Sinica
