Chau-Chung Han

E-mail cchan@po.iams.sinica.edu.tw
Office 125
Tel. of office +886-2-2366-8235
Laboratory NB11
Tel. of Lab. +886-2-2366-8249,

B.S., Chemistry, 1980, National Taiwan University, Taiwan
Ph.D.,Chemistry, 1987, Stanford University, USA

Postdoctoral Fellow, Department of Chemistry, Yale University (1987–1989)
Associate Research Fellow, IAMS, Academia Sinica (1984–)
Adjunct Associate Research Fellow, Genomics Research Center, Academia Sinica (2004–)

Mass spectrometry-based proteomics research
Signal transduction
Gene expression correlation of cell cycle
Development of new bioanalytical research tool

"Identification of Enterobacteriaceae Bacteria by Direct Matrix-assisted Laser Desorption/Ionization Mass Spectrometric Analysis of Whole Cells", Eric C. Lynn and Chau-Chung Han et al., Rapid Commun. Mass Spectrom. 13, 2022 (1999).
"Characterizing the Transmission Properties of an Ion Funnel", Eric C. Lynn and Chau-Chung Han et al., Rapid Commun. Mass Spectrom. 14, 2129 (2000).
"Solid-Phase Extraction and Elution on Diamond (SPEED): A Fast and General Platform for Proteome Analysis with Mass Spectrometry," Wei-Hao Chen, Sheng-Chung Lee, Sahadevan Sabu, Huei-Chun Fang, Shu-Chien Chung, Chau-Chung Han, and Huan-Cheng Chang, Anal. Chem.78, 4228-4234 (2006).
"Peptide analysis: Solid phase extraction–elution on diamond combined with atmospheric pressure matrix-assisted laser desorption/ionization–Fourier transform ion cyclotron resonance mass spectrometry," Sahadevan Sabu, Fu-Chia Yang, Yi-Sheng Wang, Wei-Hao Chen, Meng-Ing Chou, Huan-Cheng Chang, Chau-Chung Han, Analytical Biochemistry 367, 190–200 (2007).
"Expression of proteins with dimethylarginines in Escherichia coli for protein-protein interaction studies," Cheng-Hsilin Hsieh, San-Yuan Huang, Yu-Ching Wu, Li-Fan Liu, Chau-Chung Han, Yi-Chen Liu, and Ming F. Tam, Protein Science 16 (5): 919-928 (2007).
"Mass production and dynamic imaging of fluorescent nanodiamonds," Yi-Ren Chang, Hsu-Yang Lee, Kowa Chen, Chun-Chieh Chang, Dung-Sheng Tsai, Chi-Cheng Fu, Tsong-Shin Lim, Yan-Kai Tzeng, Chia-Yi Fang, Chau-Chung Han, Huan-Cheng Chang & Wunshain Fann, Nature Nanotechnology, 284-288 (2008).
"Preparation and characterization of green fluorescent nanodiamonds for biological applications," Wee TL (Wee, Tse-Luen), Mau YW (Mau, Yi-Wen), Fang CY (Fang, Chia-Yi), Hsu HL (Hsu, Hsiang-Ling), Han CC (Han, Chau-Chung), Chang HC (Chang, Huan-Cheng), DIAMOND AND RELATED MATERIALS, 2009, 567-573.
"Reversible Acetylation Regulates Salt-Inducible Kinase (SIK2) and Its Function in Autophagy", Fu-Chia Yang; Bertrand Chin-Ming Tan; Wei-Hao Chen; Ya-Huei Lin; Jing-Yi Huang; Hsin-Yun Chang; Hui-Yu Sun; Pang-Hung Hsu; Gunn-Guang Liou; "C.-K. James Shen; Ching-Jin Chang; Chau-Chung Han; Ming-Daw Tsai; Sheng-Chung Lee, J Biol Chem, 2013, 288(9): 6227-37.
"Improved Mass Spectrometric Analysis of Membrane Proteins Based on Rapid and Versatile Sample Preparation on Nanodiamond Particles", Minh D. Pham,, Steve S.-F. Yu, Chau-Chung Han, Sunney I. Chan, Anal. Chem., 2013, manuscript in final revision.
"Roadmap for fragmentation of protonated methylarginines in the gasphase" Sahadevan Sabua, Chau-Chung Han, Int. J. Mass Spectrom., 2015, 379, 121-132.