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BIOPHYSICS AND BIOANALYTICAL TECHNOLOGY GROup
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Education:
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B.S., National Taiwan University (1969)
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M.S., The University of Chicago,
USA (1971)
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Ph.D., The University of Chicago,
USA (1974)
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Experience:
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Research Staff Member, Oak Ridge National
Laboratory (1974–1989)
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Senior Research Scientist, Oak Ridge National
Laboratory (1989–2005)
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Research Fellow & Key Technology Division
Head, GRC, Academia Sinica (2005–)
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Distinguished Research Fellow & Deputy
Director, GRC, Academia Sinica (2006–)
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Adjunct Professor, Department of Chemistry,
National Taiwan University (2006–)
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Adjunct Distinguished Research Fellow,
Institute of Atomic & Molecular Sciences,
Academia Sinica (2006–)
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Research Interests:
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Development of novel mass
spectrometry
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Kinetics and dynamics of desorption and ionization of biomolecules
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Microarray technology
development
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Bio-nanoscience and
bio-nanotechnology
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Laser trapping and laser tweezers for a single cell interaction
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Laser spectroscopy and non-linear
processes
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New DNA sequencing technologies
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Representative Publications:
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“Metabolisms:
A New Class of Plant Metal-binding
Proteins”,
R. K. Gupta and C. H. Chen et al., J.
Protein Chem. 21, 530 (2003). |
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“Rapid
MALDI-TOF Mass Spectrometric Method for
Detection of Specific Polymerase Chain
Reaction Products by Utilizing the 5'-3'
Exonuclease Activity Thermus Aquaticus DNA
Polymerase”,
N. R. Isola and C. H. Chen et
al.,
Rapid Commun. Mass Spectrom. 17,
532 (2003).
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“Biotin
Enhanced Fragmentation for Direct DNA
Sequencing Using MALDI”, Z.
Liu and C. H. Chen et al.,
Eur. J. Mass Spectrom. 9, 213
(2003).
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“Detection
of Trinucleotide Repeat Containing Genes by
Matrix-assisted Laser Desorption/Ionization
(MALDI) Mass Spectrometry”, C. H. Chen et al., Method Mol. Biology 217, 91 (2004).
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“Detection
and Quantification of Copper-denitrifying
Bacteria by Quantitative Competitive PCR”, X. Y. Qiu and C. H. Chen et al., J. Microbiol. Methods 59, 199 (2004).
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Institute of Atomic and Molecular Sciences, No. 1, Roosevelt Rd., Sec. 4, Taipei, 10617, Taiwan or P.O. Box 23-166 Taipei, 10617, Taiwan
Tel: 886-2-2362-0212 Fax: 886-2-2362-0200 E-mail: office@po.iams.sinica.edu.tw
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