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BIOPHYSICS AND BIOANALYTICAL TECHNOLOGY GROup

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gENOMIC TECHNOLOGY LABORATORY
Supervisor:
Dr. Chung-Hsuan (Winston) Chen
Office: 2nd Floor, Genomics Research Center
Tel: +886-2-2789-9930 ext.327
Email: winschen@gate.sinica.edu.tw 

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 Education:

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B.S., National Taiwan University (1969)

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M.S., The University of Chicago, USA (1971)

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Ph.D., The University of Chicago, USA (1974)

 Experience:

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Research Staff Member, Oak Ridge National Laboratory (1974–1989)

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Senior Research Scientist, Oak Ridge National Laboratory (1989–2005)

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Research Fellow & Key Technology Division Head, GRC, Academia Sinica (2005–)

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Distinguished Research Fellow & Deputy Director, GRC, Academia Sinica (2006–)

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Adjunct Professor, Department of Chemistry, National Taiwan University (2006–)

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Adjunct Distinguished Research Fellow, Institute of Atomic & Molecular Sciences, Academia Sinica (2006–)

 Research Interests:

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Development of novel mass spectrometry

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Kinetics and dynamics of desorption and ionization of biomolecules

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Microarray technology development

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Bio-nanoscience and bio-nanotechnology

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Laser trapping and laser tweezers for a single cell interaction

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Laser spectroscopy and non-linear processes

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New DNA sequencing technologies

 Representative Publications:

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“Metabolisms: A New Class of Plant Metal-binding Proteins”, R. K. Gupta and C. H. Chen et al., J. Protein Chem. 21, 530 (2003).

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“Rapid MALDI-TOF Mass Spectrometric Method for Detection of Specific Polymerase Chain Reaction Products by Utilizing the 5'-3' Exonuclease Activity Thermus Aquaticus DNA Polymerase”, N. R. Isola and C. H. Chen et al., Rapid Commun. Mass Spectrom. 17, 532 (2003). 

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“Biotin Enhanced Fragmentation for Direct DNA Sequencing Using MALDI”, Z. Liu and C. H. Chen et al., Eur. J. Mass Spectrom. 9, 213  (2003). 

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“Detection of Trinucleotide Repeat Containing Genes by Matrix-assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry”, C. H. Chen et al., Method Mol. Biology 217, 91 (2004). 

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“Detection and Quantification of Copper-denitrifying Bacteria by Quantitative Competitive PCR”, X. Y. Qiu and C. H. Chen et al., J. Microbiol. Methods 59, 199 (2004). 

 

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